Collagen molecular phenotypic switch between non-neoplastic and neoplastic canine mammary tissues
نویسندگان
چکیده
منابع مشابه
Multiplex Gene Expression Profiling of 16 Target Genes in Neoplastic and Non-Neoplastic Canine Mammary Tissues Using Branched-DNA Assay
Mammary gland tumors are one of the most common neoplasms in female dogs, and certain breeds are prone to develop the disease. The use of biomarkers in canines is still restricted to research purposes. Therefore, the necessity to analyze gene profiles in different mammary entities in large sample sets is evident in order to evaluate the strength of potential markers serving as future prognostic...
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The aim of this study was to evaluate the localization of collagen modifying enzymes (CMEs) on fibroblastic reticular cells (FRCs) and follicular dendritic cells (FDCs) in non-neoplastic lymphoid tissues and various malignant lymphomas. The expression of prolyl 4-hydroxylase 1 (P4H1), lysyl hydroxylase 3 (LH3), and protein disulfide isomerase (PDI) was frequently observed on FRCs and FDCs in th...
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apparent correlation between the susceptibility of a strain to mammary tumor development and the ability of its normal mammary gland receptors to bind estradici. The receptor appears to be in the parenchyma! elements of the gland. The spontaneous mammary tumor showed binding capacities significantly lower than the normal gland, based on wet weight tissue and DNA content. There is no correlation...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-021-87380-y